Rhapsody

computationally predicting effects of saturation mutagenesis
In silico saturation mutagenesis
perform a complete scan of all possible 19 amino acid substitutions at each site on a human sequence. See example: H-Ras.
Variants on custom PDB structure
perform saturation mutagenesis analysis on a specific conformer, homology model or homologous structure (in case human structure is not available).
Batch query of mixed variants
obtain predictions for a list of human missense variants from various protein sequences. See an example here.