Rhapsody

In silico saturation mutagenesis

scan of all possible amino acid substitutions in a human protein sequence

update (June 28th, 2021): --- ISSUE RESOLVED --- Due to a recent update to the PolyPhen2 webserver, the submission system wasn't working properly for the past couple of days, but the issue has been since resolved. We apologize for any inconvenience this may have caused and we thank Dr. Adzhubey (main developer of PolyPhen2) for the help in resolving the issue.

Uniprot sequence ID

type the Uniprot accession number of a human sequence or leave blank to run test case.
optional: add a specific position for single-site scanning, e.g. P01112 100

Invalid query

include EVmutation feature

use custom PDB structure

include "environmental effects"

email

you'll be notified when results are ready

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